I went with Camp Randall. Penn State is intimidating on the inside, but around the stadium there is nothing. Plus, buying beer in PA is an awful experience.
I lived about 2 blocks from Camp Randall the year after I graduated from
OSU, and the stadium is nice and the fans are nuts. Best renditions of the wave you'll ever see.
I've been to East Lansing 3 times, and enjoy it every time. The one thing most other schools have that we don't is a dedicated student section. Block O is a joke compared to putting 20-30,000 drunk college kids together.